There are two major classes of E3s that differ in the mechanism by which they mediate the transfer of ubiquitin to substrates.
Two different aquaporins were later found to play a major role in the mechanism by which human kidneys concentrate urine and return the extracted water to the blood.
Therefore, T-cell-mediated activation of Wnt signaling in osteoblastic cells plays a key permissive role in the mechanism by which iPTH increases bone strength, suggesting that T cell osteoblast crosstalk pathways may provide pharmacological targets for bone anabolism.
Japanese physicists pitched to the international community to build the facility in Japan in 2012, after scientists at the LHC — based at CERN, Europe's particle-physics lab near Geneva, Switzerland — discovered the Higgs boson, a particle involved in the mechanism by which all others get mass.
But this is in fact a significant issue in the mechanism by which study sections can protect their sub-field from "intruders", particularly when the subject matter is unfamiliar to many members of the study section.
Consistent with the view that consciousness and action may be closely related, brain imaging studies have shown that delusions of control, often seen in schizophrenic patients, are associated with a failure in the mechanism by which the predicted consequences of an action are linked to the intended sequence of motor commands (Frith et alia 2000).
The TALA is a batch estimator, and its novelty lies in the mechanism by which it circumnavigates the need to perform global multi-sensor/multi-target data association (e.g. as necessary in [20]), which can be a computationally prohibitive combinatorial optimisation (e.g. see [22]).
The TALA is a batch estimator, and its novelty lies in the mechanism by which it circumnavigates the need to perform global multi-sensor/multi-target data association, e.g. as necessary in [20], thereby allowing the TALA to maintain computational feasibility, even for large-scale problems.
Thus, these data indicate the importance of protein interactions in the mechanism by which LAT controls TCR signal initiation.
These results suggest that ROS generation, through decreasing GSH levels, plays a key role in the mechanism by which AAP induces rat cortical neuronal death.
Furthermore, phosphorylation of the C-terminal region of Cdc10 has also been implicated in the mechanism by which the checkpoint activates MBF dependent transcription [14].
