For no pooling, the model was applied to each population in turn, for complete pooling to the joint data set.
Assuming independent and identically distributed (IID) measurements (elements in 𝒟), a factorized form for the joint data likelihood can then be written as f = ∏ i =1 I ∏ j =1 J f y ij | p j, x i, λ i ), where θ is a collection of all model parameters, i.e. p tj 's, x tic 's, and λ i 's.
Moreover, no significant differences could be observed for IL-23 in circulation or locally in the joints (data not shown).
The joint data would be used in the subsequent simulations to compute the pressure dynamic process according to previously established pneumatic model.
Although the serum TNFα concentration of BM-hIL-32 mice was comparable with those of reported human TNFα transgenic mice [ 43], no inflammatory change was observed in histological examination of the joints (data not shown).
To achieve this, we propose a weighted clustering process in the joint input output data space.
Development of ankle swelling (Fig. 2D) or histopathological changes in the joint tissue (data not shown) in B. burgdorferi-infected mice immunized with BbCRASP-2 did not differ from the control, suggesting that host BbCRASP-2 antibodies fail to influence the ability of B. burgdorferi to induce arthritis in the murine host.
Although FRI FLC had the longest mean period in each experiment, the interaction between FRI and FLC was not significant in the joint analysis (data not shown).
As expected [ 31, 32], types I and III collagens were also prominently immunolocalized in the marginal osteophytic fibrocartilaginous regions in the meniscectomized joints (data not shown).
In the method, the correlation weight joint data vector is constructed and the data vector can make the noise subspace dimension of the corresponding weight covariance matrix which is not affected by the coregistration error, thus avoiding the trouble of calculating the noise subspace dimension before estimating the InSAR interferometric phase.
