Sentence examples for in the internalisation from inspiring English sources

Furthermore, in the internalisation assay, protein might be internalised and return to the same sites via exocytosis.

The results revealed that the clathrin mediated pathway and dynamin played a role in the internalisation of these specific nanoparticles.

Thus, Homer1b declustering is directly involved in the internalisation of mGluR1.

This is in agreement with the aforementioned finding that a clathrin-insensitive entry pathway also operates in the internalisation of ACT.

Whether syndecans are involved in general receptor uptake or in the internalisation of specific receptors remains to be determined.

Stimulation of serum-starved UMSCC81B cells with EGF ligand resulted in the internalisation of EGFR from plasma membrane-like 81B-Fb cells.

In addition, the internalisation rate of tumour antigen-bound therapeutic antibodies could be of importance for the Fc-mediated effects and modulation of the cytokine milieu as demonstrated in the present study.

The effect of albumin fragments (FRALB-C) and selected albumin-derived peptides on the internalisation of In-albumin, In-minigastrin, In-exendin and In-octreotide by megalin-expressing cells was assessed.

Ligand binding to CD11b/CD18 is known to induce activation of non-receptor tyrosine kinases that promote its phosphorylation, which in turn induces the internalisation of the integrin within clathrin-coated pits [33], [34].

In chlorpromazine-treated cells the internalisation of ACT and β2 was more modest, but still detectable (≈20%) (Fig. 3 A and B, respectively), suggesting that a clathrin-independent, ACT-induced internalisation mechanism might be operating in parallel in the ACT-treated cells.

In particular, actin assembly accompanies the internalisation of coated pits at the plasma-membrane (PM) in yeast (Engqvist-Goldstein and Drubin, 2003), and a burst of localised actin polymerisation accompanies the cycling of synaptic vesicles.