The IR of UC-associated dysplasia was significantly increased in the fourth decade compared with the third decade (17.7 vs. 11.7 per 1,000 patient-years; χ, P=0.01).
There was a non-significant increase in the IR of Dukes' A or B in patients whose CRC was detected during surveillance colonoscopy or at the time of colectomy performed for dysplasia in the fourth decade compared with the third decade (3.0 vs. 1.3 per 1,000 patient-years; P=0.06).
This revealed that although the overall CRC IR had decreased over the first three decades, there was a nonsignificant increase in CRC IR in the fourth decade (4.9 per 1,000 patient-years) compared with the third decade (3.7 per 1,000 patient-years; χ, P=0.30; Figure 3a).
However, this was followed by a significant increase in the fourth decade (3.2 per 1,000 patient-years) compared with the third decade (1.3 per 1,000 patient-years; χ, P=0.045).
Osteoarthritis usually begins in the fourth decade of life and slowly progresses with increasing age.
It affects both sexes equally and usually becomes manifest in the fourth decade of life.
The grown-up Mr. Weller has his thrills: in the fourth decade of his career he's still an unregenerate rocker.
For those who stay behind, life, in the fourth decade of civil war, is dangerous and difficult.
And they're still making challenging music in the fourth decade of their career, when most other bands of their generation have become little more than their own tribute acts.
The spare arrangement and Bush's entirely straight-faced delivery wring genuine intimacy from this bizarre scenario, proving that, in the fourth decade of her career, she had lost none of her imaginative power.
In the fourth decade of the twentieth century, Streptomyces was recognized.
