In the first instance, altered levels of NMT expression in transgenic parasites were confirmed by Western blot, using TcTryR as a loading control.
This paper presents results obtained from a study of a new thick section laser-cutting process capable of cutting sections up to 50 mm thick in the first instance, with power levels less than 2 kW whilst maintaining excellent cut quality.
This type of cancer typically metastasizes in the first instance at the level of regional lymph nodes and lung, in the late stages in the bone marrow.
However, this is likely to be an artefact of the treatment regimes used on the unit, where the policy is to: aim for plasma levels of 0.35 mg/l in the first instance; to increase the dose to levels of 0.50 mg/l if there is an inadequate response; and if there is still insufficient benefit to augment with another medication.
A stepped-care treatment model seeks to treat patients at the lowest appropriate level in the first instance, only 'stepping up' to intensive/specialist services if clinically required.
Multivariate modelling will take the form of a multilevel or hierarchical model in the first instance; with hospitals at the top level.
Such a system is to be voluntary in the first instance, except where general or high level health claims are made or equivalent endorsements/trade names/marks appear on the label, in which case it should be mandatory.
Since plant defense signaling mechanisms may well be selected to respond as rapidly as possible to the presence of herbivores, their initial response is probably modulated by physiological means in the first instance, rather than by changes in expression levels.
In the first instance, to determine which genes had expression levels that were copy number-regulated, aCGH data were utilized as a continuous variable and cbs-smoothed ratios were correlated with microarray-derived gene expression levels.
I'm convinced we have a core group who can perform at the highest level, but in the first instance international riders will bolster the numbers". There will, therefore, be a number of foreign signings to ensure competitiveness from day one, which is likely to come in 11 months at the Tour Down Under in Australia.
