"in the first instance however" is a grammatically correct phrase and can be used in written English.
It is typically used to introduce a contrast or contradiction in the first part of a sentence, followed by a counterpoint in the second part. Example: In the first instance, however, the company's profits were declining. Despite this setback, the CEO remained optimistic about the future growth potential.
Mueller was hired in the first instance, however, to superintend an ongoing FBI counterintelligence investigation.
Reference [21] is another paper in the literature, which may seem similar to this work in the first instance; however, there are many differences: theirs use Stockham FFT algorithm, ours is based on Cooley-Tukey radix-2 FFT algorithm.
Additional information: "Searches for the review were conducted without language restriction in the first instance; however, included studies were limited to those published in English.
In the first instance, however, we need to establish the actual impact of hormones generated by adipose tissue on bone mass [ 73].
In the first instance, however, the key questions for tool development are: do the categories within the tool cover those factors critical to local public health?; do the questions within each category capture the important dimensions of the concept?; and, do the scales provide meaningful answers to those questions?
Such studies therefore rely on a robust and quantifiable phenotypic assay for the disease model in the first instance; however, this is a potentially very valuable and unbiased approach to understanding how in the interaction between genes can influence pathogenic pathways.
In the first case, however, against Australia, New Zealand and South Africa, England conceded a first-innings lead in all but one instance, won only twice as a result and drew four.
However in the first instance, we would expect those concerns to be taken forward by the lawyers involved.
However in the first instance, population diversity and ethnic differences in disease risk present an avenue of research towards understanding the underlying disease genetics [15].
However, in the first instance [13], the reported effectiveness of this compound (i.e. CRT0044876 or 7-nitro-1H-indole-2-carboxylic acid) has not been reproduced [14].
However, in the first instance, any composite rating system must be based on clinically meaningful subgroups, with definable endpoints.
