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Immunoglobulin levels and isotype recovery sequence (IgM>IgG>IgA) in responders correlated with the expected mode of action of blinatumomab, with initial B-cell depletion leading to decreased immunoglobulin levels during and after treatment and a subsequent return of IgM-secreting plasma cells originating from newly developed naive B cells.
These results indicate that the addition of an electron withdrawing group in the side chain of l-arginine-derived NOS inhibitors must be considered during inhibitor design depending on the expected mode of interaction with the enzyme.
In other words, if each module is designed to be of minimum weight with respect to the expected mode of response, then their assembly would also be of minimum weight with respect to the same performance requirements.
Thus, dimerization of decoron and biglycan might seem incompatible with the expected mode of interaction of these PGs with collagen [32].
The expected mode of failure for the MSS-cowling assembly was metal fatigue under random vibrations.
When short-term flings are the expected mode of sexual interaction, we tend to regard other, more slow-paced forms of romance as abnormal.
In an effort to enhance the external validity, the treatment allowed the therapist a range of 8 12 weekly sessions with an expected mode of 10.
But their comeuppance never arrives in the expected ways.
"It doesn't always happen in the expected ways.
Chisholm does this in the expected ways.
Toss this one in the "expected but darn useful" column.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com