The comparison of its results with measured values indicates the improvement of accuracy in comparison to the existing methodology, resulting in reduction of the design margin.
In summary, the chemoenzymatic method we have described for the synthesis of enantioenriched α-hydroxy carboxylic acids is a valuable addition to, and in some cases offers advantages over, the existing methodology that has been used to prepare these valuable chiral building blocks.
Concerns have also arisen about the existing methodology for measuring catastrophic spending and impoverishment in the literature.
As a result, in spite of the existing methodologies, still the most common and reliable way to identify proximal regulatory regions in genomes is the analysis of a few nucleotides (typically up to 1000) immediately upstream of annotated transcription start sites (TSSs), which likely constitutes the proximal promoter.
In this paper, we review the recent endeavours in this direction, and summarize the existing methodologies and computational tools for network-based analysis of complex diseases and molecular relationships among apparently different disorders and human disease network.
In doing that, the work uncovers the advantages and disadvantages of the existing methodologies so that future algorithms could be designed in retaining the advantages of the existing methodologies while avoiding the presented weaknesses.
Models and methodologies: As presented previously, the existing methodologies for security testing contain several variations in their characteristics, objectives, and procedures; however, those methodologies also have limitations regarding target scenarios since they are tailored to serve distinct purposes.
We believe this promoter-probe methodology may support the existing methodologies to the identification of novel virulence factors of pathogenic Leptospira spp. Bacterial strains and constructs are listed in Table 1.
The two-stage design was intended to overcome the limitations inherent in existing methodology; namely that questionnaires and surveys are typically constructed without first exploring patients' own opinions on the subject in question.
The April 2009 document said that, in the absence of any existing methodology to study the problem, EDF should "prepare an internal document" on possible solutions, that would "not be transmitted to the A.S.N".
