In a Δ rad59 context, a 2.5-fold increase in the duplication rate was observed, which suggests that inactivation of the SSA pathway may favour the occurrence of duplications.
The high frequency of fixed duplications in the glycolysis pathway may reflect the fact that it is the only cytoplasmic pathway in the system.
This is not due to tandem duplications, as most genes in the same pathway that are adjacent in the genome do not arise from duplication events [ 27].
Several cases of lineage-specific duplication were also observed in the pteridine pathway.
In the pteridine pathway, two cases of duplicated genes originating from the FSGD as well as several lineage-specific gene duplications were observed.
Having established that CAP350 stabilizes procentrioles early in the assembly pathway of a new centrioles, we investigated whether the centriole duplication initiation process contribute to procentriole stability.
Since this gene acts late in the ergosterol pathway, it is considered to have evolved as a result of duplication and diversification of the CYP51 gene [ 8].
In many cases, accumulation of metabolic intermediates would be toxic to plants and simultaneous duplication of consecutive steps in the metabolic pathways is required and favoured.
Another key mutational process is duplication of proteins already participating in the pathway.
