Sentence examples for in the disorganization of from inspiring English sources
The IE1 protein of human cytomegalovirus (HCMV), the E4-ORF3 profein of adenovirus 5, the BZLF protein of Epstein Barr virus (EBV), and the L-HDAg protein of hepatitis delta virus (HDV) have all been implicated in the disorganization of PML protein and PML NBs [13] [19].
Colistin is rapidly bactericidal for Gram-negative bacteria, interacting with the lipid A components of lipopolysaccharide (LPS), resulting in the disorganization of the outer membrane of bacteria [ 14].
This phenotype can be reversed by inhibition of FAP enzymatic activity during matrix production resulting in the disorganization of the ECM and impeded tumor invasion.
Cholesterol depletion results in the disorganization of lipid raft microdomains and also the dissociation of proteins [ 18] that are bound to the lipid raft.
Our data also showed that MIF induced actin polymerization and VE-cadherin disorganization (Fig. 2A) within 30 min, indicating that MIF promoted actin rearrangement and resulted in the disorganization of junction proteins.
These defects in cell morphology may prevent the normal symmetrical mitotic division and result in the disorganization of metaphase progenitors, which often forms rosette-like clusters near the ventricular surface (Fig. 8E, asterisk).
In agreement with the disorganization of the mitochondrial complex activities in DIO old rats, there was a decrease in transcript levels of PGC1α, a transcriptional co-activator playing a multifaceted role in the regulation of mitochondrial energy metabolism and biogenesis.
Moreover, these transfectants showed the suppression of motile activity assayed by phagokinetic tracks in addition to the disorganization of actin filaments observed by a confocal imaging system.
There was a significant increase in the levels and the disorganization of F-actin stress fibers in caspase-14 expressing cells compared to control.
In conditions that produced the disorganization of the F-actin or microtubule cytoskeletons (Figs.
In addition to suggesting that the disorganization of basement membranes may play an important role in disease, this work also provides a method for investigating the structure of the basement membrane in diverse types of tissue.
