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Macron and Putin's personal relationship will be key factor in the difficult issues of Syria and Ukraine.
"I have confidence that our European colleagues fully appreciate what is at stake in the difficult issues they are now confronting and that, over time, they will take all necessary and appropriate steps to address those issues effectively and comprehensively", he said.
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All in all, the visit did not live up to the media hype, but it served its purpose of maintaining high-level engagement with Pakistan in the hope that incremental progress could be made in resolving the difficult issues that bedevil the bilateral relationship.
Fox has also grasped the nettle in the difficult issue of dealing with the steep declines of regional newspaper operations.
We conclude that, while the domains themselves need further work, the approach provides a helpful starting point in the difficult issue of reflecting population preferences for a large number of social care outcome domains.
In the coming weeks and months, Congress will be engaged in the difficult issue of how best to reform health care in America.
The culprit is the flattening of federal science funding that has occurred in recent years and the difficult issues involved in the fair and equitable dissemination of those dollars.
But, in part because of the difficult issues brought up by high-profile cases, degrees in the subject are more popular than ever, according to the country's top-ranking university social work department.
It undermines the trust and confidence so badly needed in creating the appropriate environment for successful negotiations, especially on the difficult issues involved in the permanent status talks.
You cannot duck the difficult issues in the middle of an election campaign.
Justice Kennedy asked hard questions of both sides, suggesting that he is still grappling with the difficult issues in the case.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com