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Given the critical importance of EMPs in the correct development of enamel, we investigated the amelogenin protein structure of strepsirrhines using the mouse amelogenin cDNA backbone.
Moreover, the worse performance of the RhoE gt/gt mice in a broad range of motor tests indicates that RhoE could be involved in the correct development of the motor function.
Restoring CD expression, using an MPO-non-matching mutated mRNA, partially rescued the normal phenotype, confirming the indispensable role of CD in the correct development and integrity of the somitic musculature.
The present study provides the first evidence of an active and indispensable role of CD in the correct development and function of the skeletal musculature in zebrafish, demonstrating the involvement of CD in congenital myopathies.
Epigenetic mechanisms are also believed to play a crucial role in the correct development of placenta and fetus by affecting gene expression patterns 47, 48 as well as to play a role in the future development of asthma and allergy 47, 49.
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The localization of Hsp60-like BBS proteins at the cilium basal body and at the centrosome [ 26- 28] suggests that they may also interact and associate with, for example, cytoskeleton structures in promoting the correct development of cilia [ 28, 57].
The ceh-20; unc-62 double mutant, strain AW679, displayed much more extensive seam hyperplasia, up to 70 seam cells per side, extending throughout the length of the animal (Fig. 2), suggesting that CEH-20 and UNC-62 interact in a complex to control the correct development of the seam lineage.
These findings underline key regulation of the Def locus in controlling the abscission process through the correct development of the hilum double palisade layer as a prerequisite for AZ development in wild type pea seeds.
Unlike MRFs, this gene is up-regulated in the electric organ of the two species analysed here, as well as in other electric fish species [ 20, 21], and it is also important for the correct development of posterior somites in D. rerio [ 29].
This dual role for the chemical and electrical components is not unprecedented as transient gap junction communication is needed for the correct development of chemical synapses in the optic lamina (Curtin et al., 2002).
It is a developmental disorder that arises due to failure in migration of enteric neural crest cells into the intestinal tract or due to a failure in survival, proliferation, or correct development of enteric neurons once they reach the gut [1].
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