Sentence examples for in the complementarity from inspiring English sources
Marriage is rooted in the complementarity of man and woman.
This analysis further builds our confidence in the complementarity result.
Antibodies typically accumulate mutations in the complementarity determining region (CDR) loops, which usually contact the antigen.
In this work, position-specific frequency and hierarchical clustering analysis are used to explore the statistical pattern of the residues in the complementarity determining regions of human antibodies.
Recent work has demonstrated that antibody phage display libraries containing restricted diversity in the complementarity determining regions (CDRs) can be used to target a wide variety of antigens with high affinity and specificity.
The introduction of aminoethyl-8 (A-8) reagent which renders cysteine residues in the antibody to become substrates for trypsin digestion significantly increases the sequence coverage of the antibody, especially in the complementarity determining regions (CDRs).
The implicit complementarity problem was introduced into the complementarity theory in [3] as a mathematical tool in the study of some stochastic optimal control problems.
Finally, these two contributions are brought together in The Complementarity-Capability Matrix, where we propose seven complementarity strategies and resources and capabilities necessary to achieve them.
Moreover, compared to binding assay, cell-based bioassay could detect the impact of chemical modifications, such as deamidation in the complementarity-determining region or the Fc region of the molecule on its potency.
A putative Asp serine (Ser) isomerization motif was identified in the complementarity-determining region of a humanized monoclonal antibody and shown to be a developability risk using accelerated stability analyses.
This work presents preformulation characterization data on the effect of pH, NaCl concentration, and various cationic excipients on the physical and chemical stability of a Fab molecule with multiple negatively charged Asp residues in the complementarity-determining region.
