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We demonstrate that tFCS detects changes in the compaction of reconstituted nucleosome arrays and can assay transient protein-mediated interactions between distant sites in an individual DNA molecule.
The chromatin assembly results in the compaction of DNA preventing access and the binding of transcription factors.
Michrafy, M.S. Kadiri, J.A.D. Dodds, Wall friction and its effects on the density distri-bution in the compaction of pharmaceutical excipients, Chem.
This variation in the compaction of the corpse creates a variation in the concentration of Hg with the approximate shape of a sine wave.
These results suggested that the MsDps2 protein is involved in the formation of the nucleoid structures and probably plays a role in the compaction of the M. smegmatis nucleoid similar to the E. coli Dps protein.
At this stage, factors such as the TGF-β superfamily (TGF-β and BMPs) are known to play critical roles in the compaction of progenitors cells and shaping of the condensations [21].
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The Caspr staining of paranodes, which reappears in remyelination, plus the compaction of the myelin sheaths seen by electron microscopy, suggests that these remyelinated fibres are mature.
As shown in Fig. 5E, the compaction of floating collagen I gel was significantly greater in ACTN4 KD fibroblasts comparing to WT ACTN4.
In order to investigate the compaction of homogeneous and composite powders under carefully controlled conditions, idealized two-dimensional compacts were constructed using rods of aluminum and hardened steel.
In a similar manner, the compaction of such a fiber was shown to increase from 11 nmcleosomes/11 nm for 35 nm diameter fibers to 16 nmcleosomes/11 nm for 45 nm diameter fibers (Fig. 1).
Brownian dynamics simulation is run until a steady state of the chromosome compaction ratio is achieved (as shown in Figure 2C where the compaction of chromosome stabilized from ∼5 min onwards).
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