Sentence examples for in the cleaved from inspiring English sources
In this cleavage, also considered by de Leeuw and Cooper [27], the third highest oxygen in the cleaved structure is protonated instead of the top hydroxyl.
The C-terminal cleavage at Lys79∼Arg80 only slightly reduced heparin affinity (Figure 2E) consistent with the removal of just two basic residues in the cleaved peptide 80RNALAVERTASVQ92 while the N-terminal truncation had no effect on heparin binding.
Furthermore, a Mg2+ ion now coordinated by Glu 433 and Asp 506 is bound to bridging and apical oxygens of the scissile phosphodiester moiety facilitating tyrosyl attack by stabilizing both the incipient 3'-OH leaving group and tyrosyl phosphate group, as seen in the cleaved complex (Figure 3B).
We did not observe any significant increase in the cleaved ATF6f (productoduct arising from transfected FLAG-tagged ATF6 (p90) in 3a expressing cells as compared to control cells; however, treatment with thapsigargin led to increased levels of the p50 form (not shown).
In line with these data, knockdown of p63 in both SCC9 and iPrEC cells resulted in an increase in the cleaved caspase 3 levels and a concomitant decrease in the expression total caspase 3. Accordingly, cleaved poly (ADP-ribose) polymerase (PARP) protein levels were increased after p63 knockdown (Figure 2D).
We also found similar siRNA biogenesis patterns in the cleaved TAS3 and TAS4 transcripts.
In concordance with Skoff et al. (2001), we showed an increase in the cleaved-caspase-3+ cells in the SVZ after H/I.
The concentration of glutathione plays an important role in controlling the cleaved efficiency.
In addition The cleaved crosslinker alters peptide mass and can prevent recognition by standard MS algorithms [24].
In addition, the cleaved form and a punctuate distribution for endogenous LC3B were observed during LAPTM5-induced cell death in SH-SY5Y cells (Supplementary Figure S6).
In fact, the cleaved form of caspase-12 was markedly detected from 18 h up to the end of recovery.
