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CLE42 is also a dodecapeptide (His-Gly-Val-Hyp-Ser-Gly-Hyp-Asn-Pro-Ile-Ser-Asn) and differs from CLE41 only in the 2nd position.
T in the 2nd position has advantages over U, as its 5 СН3 group is important for interaction with hydrophobic amino acids (see Consequence 3. The molecular mechanism of genetic code arising).
This increase in hydrophobicity is more pronounced in codons with editing in the 2nd position.
Hence it makes sense that information should be encoded in the 2nd position initially.
The Asp residue in the 2nd position of (I/L/V D(S/T G is highly conserved and can only be replaced by Glu, indicating that the negative charge is essential.
The phage with insert in the 2nd position formed unexpectedly bright plaques, but sequence analysis showed the presence of the nonsense codon immediately after GFP gene, therefore this phage produced free GFP non exposed on the phage capsid.
Similar(53)
Large hydrophobic residues in the P2 position and positively charged residues in the P1 position of the substrate are usually preferred.
The neutron flux was ∼3.5×104 cm−2 s−1 in the CH2 IP position.
Yet when the ball was pinged at him in the No10 position it pin-balled away.
Even Lukas Podolski was excellent in the No10 position: two goals raised his tally to seven.
Or, "To have babies, I need to mate with another hermaphrodite in the 69 position".
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