It is interesting to note that in a previous work of ours [2] it was showed that in this specific sample of animals there was no, or scarce, autocorrelation for both angles and distances, which strengths reliability of our results.
The mRNA content of each gene was normalised to total single-stranded cDNA in the specific sample.
We thus proposed to remove indels detected in a specific sample that were also found in the set of indels filtered by QDth and VARWth from other samples.
If a TFBS was not over represented in a specific sample, that TFBS was assigned an score of N+1 so as to serve as a proxy for being highly under represented.
Similar to PBC, we observed that BMIQ significantly reduced the bias of type2 values (Fig. 3), although there was no improvement over PBC itself, presumably owing to the fact that in these specific samples the methylated type1 peak was well defined, a scenario in which PBC works well.
In addition, other studies are consistent with ours in showing that specific clinical characteristics of the sample may affect neuroanatomical findings (Frodl et al., 2002; Ballmaier et al., 2008; MacQueen et al., 2008).
Z-score measures the number of standard deviations that a gene expression in a specific sample is from the mean expression of this gene over all samples.
During the ChIP process, DNA is initially cross-linked in a specific sample to the protein that binds to it.
There was also no indication in our sample that specific recurrent CNVs, other than 22q11.2 deletions, were associated with expression of schizophrenia.
The present work consisted of direct measurement in autopsy cases in a population specific sample.
