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"We decided to do it down here because we're down here and part of the area that was affected, not in terms of structural damage but psychological," Mr. Sniedze said.
In terms of structural damage, 851 homes were impacted in varying degrees.
In RA, a persistent disease activity even at a moderate level has been shown to be deleterious in terms of structural damage and/or reduction in work capacity.
Although a proportion of early patients will have good responses to traditional DMARDs, TNF-blocking drugs provide more rapid control of inflammation and better long-term outcomes (in combination with methotrexate), both clinically and in terms of structural damage.
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Presumably different genetic factors are involved in developing RA and in progression of structural damage.
Abatacept therapy resulted in inhibition of structural damage progression over time.
Another interesting point is whether a continuous control of signs and symptoms in the long term translates into true disease modification or prevention of structural damage and ankylosis.
In addition to controlling inflammation, prevention of structural damage is a key objective of antirheumatic therapy.
Rituximab has been shown to inhibit progression of structural damage in RA over 2 years, and continues to inhibit joint damage with long-term treatment [ 39, 84].
He also argues that these basement developments serve a useful structural function: "We are dealing with 200-year-old buildings, with all sorts of structural damage in them already.
Engineering demand parameter (EDP) is the output of the IDA analysis that elicits the state of structural damage in terms of its response under different earthquake records.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com