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They added proteins that had been bound to the ER membrane, reasoning that only proteins involved in tagging would bind to the ubiquitin-tagging machinery in the filter.
Mice designed to lack tagging proteins — called complement proteins — had problems both in clearing cellular debris and in tagging and pruning their synapses.
Magnum's partner in the project is Tagasauris, a company that specializes in tagging archival pictures.
Even the apparently benevolent techniques of modern researchers in tagging whales has been shown to have an adverse effect.
It has occasionally surfaced, in the real world, with seapunk-themed parties and bands, but the real joy remains in tagging and sharing the trippy nautical images.
"I just thought there was something grotesque in tagging #mountofash next to a mount of ash in Majdanek, or in making a 'sexy' or 'seductive' face next to a crematorium.
"Luckily for us, they haven't figured out that they are stronger than us," Dr. Mitani said, explaining that there was no danger in tagging along behind a file of chimps on the warpath.
I don't generally believe in tagging middle-aged people with the deeds of their youth, but there has been remarkable consistency between young lawyer Roberts and Chief Justice Roberts.
He specialized in tagging the A-line subway, but he was said to have put his tag on every subway line more times than anyone else, making him an "all-city king".
The IFG also flags up worries about outsourcing some services given previous failures, such as allegations that security companies had been overcharging for their services in tagging prisoners on probation and the shortcomings of security during the London Olympics which meant the British army was called in to plug the gap.
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The simplicity of this strategy contrasts with other knock-in tagging methods, where the tag sequence is directly fused to the endogenous exon, what requires customization of the junction point [37], [38], [39].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com