Biochemical data in support of this model are also presented.
In support of this model, recent experimental findings of various research groups are also provided.
In support of this model, the hyper-mutagenesis observed in a polA1 polBΔ1strais is completely dinB-dependent.
In support of this model, overexpression of dTcf inhibits Mad-dependent suppression of Wg target gene expression in vivo.
In support of this model, it was previously reported that Rsp5-dependent ubiquitination of cargo must occur at the MVB stage for proper sorting into MVBs [57].
In support of this model, expression of multiple Shh target genes is decreased in GNPs from mice with reduced levels of MDM2.
In support of this model, endogenous PIDD mRNA levels are elevated in SOX or muSOX-expressing cells but the transcript becomes sensitive to shutoff when overexpressed.
In support of this model, modulation of T1D pathogenesis in animal models has proved successful through early intervention with a variety of dietary alterations [8].
In support of this model, we observed that osteoclast differentiation was increased in the absence of Id1, leading to increased secretion of CTSK.
In support of this model, we observed robust repression of genes encoding transcription factors and enzymes involved in fatty acid and triglyceride synthesis, triglyceride hydrolysis and sebocyte differentiation.
In support of this model we show that dimerisation is sufficient to induce ROR2 activation and that Wnt5a induces ROR2 phosphorylation.
