Furthermore, the sensitivity of rfs-1 animals to IR is relatively weak compared to deficiency in the core HR component BRC-1, whereas sensitivity of rfs-1 and brc-1 animals to crosslinking agents is virtually indistinguishable, in support of the greater specificity of RFS-1/RIP-1 toward stalled replication fork substrates (Ward et al., 2007).
Because pristane has previously been demonstrated to induce the production of anti-Su antibodies in approximately 50% of BALB/c mice [ 25], we used an anti-Su serum from a pristane-induced autoimmune mouse as further evidence in support of the potential specificity of anti-Su serum for GWBs.
In support of the improved sensitivity and specificity of our procedure, we identified more than 50 F-Oct4-interacting proteins by mass spectrometry (Table 1).
Serological markers, especially autoantibodies with high disease specificity, have their emphasized role in support of the diagnosis of autoimmune diseases.
In support of the Surgical ICU Unit.
This study was designed to replicate and extend psychophysiological research, which has used multivariate pattern classification analysis (PCA) in support of ANS specificity.
However, Bradley et al. provided solid evidence in support of tissue specificity based on RNA-seq analysis of 16 human and 8 mouse tissues wherein they demonstrated that at least 25% of NAGNAG acceptors in mRNA were regulated in a tissue-specific manner [ 1].
Conversion of DHEA in preadipocytes is negligible, and in support of specificity, detection of OATP-D, an influx transporter of DHEAS (38), suggests that the lack of effect of DHEAS is not due to its inability to enter the cell.
However, all of those tools above have some shortcomings in terms of supporting the specificities of the PBL design and implementation.
Of significance, previously validated immunogenic tick saliva proteins including AV422 protein, calreticulin, histamine release factor, histamine binding/lipocalins, selenoproteins, and paramyosin were identified in this screen, supporting the specificity of the approach in this study.
