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Thus, effective LAVs maintain lymphoid tissue-based, effector-differentiated, SIV-specific T cells that intercept and suppress early wild-type SIV amplification and, if present in sufficient frequencies, can completely control and perhaps clear infection, an observation that provides a rationale for the development of safe, persistent vectors that can elicit and maintain such responses.
All possible genotypes for two loci must appear in the population in sufficient frequencies to allow statistical analysis [ 28].
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The surgical condition selected, i.e. unilateral closed splint bone fracture with marked exostosis and development of connective tissue induration, is a condition found in sufficient frequency to recruit a sizable clinical study in a multi-centre setting.
However, if BTS were repeatedly introduced in large numbers over multiple years (as we have been told was the case by people familiar with the initial introductions in the 1950s), then pure non-native salamanders would have been present in sufficient frequency to result in the production of high-fitness bcBTS families during the second-generation of admixture.
For instance, assuming that two independent mutations are required to confer resistance to the two component drugs, it is not known whether the mutation rate in Plasmodium spp. can produce the two mutations in one parasite (in one host) at a sufficient frequency, or whether these mutations confer fitness advantages if the two component drugs are administered at the same time.
Thus, when there is already sufficient frequency diversity in the system, the improvement in using sophisticated selection schemes which better exploit the spatial diversity is not as pronounced.
These long thin wires can isolate the longitudinal electric field component from other field components and produce sufficient frequency shift in bead-pull measurements.
Short duplications that underlie the selected lac amplifications are found in the unselected pregrowth culture at sufficient frequency to explain unstable revertants (Reams et al. 2012).
We then examined the impact on utilization for any barriers and then looked separately at those with variability and sufficient frequency to test in utilization models (i.e., geographic distance, and wait time barriers).
This difference in expression levels is likely reduced in a large population, where beneficial mutations occur with sufficient frequency.
In the following, we describe an HMM for identifying duplicon regions with sufficient frequency and length.
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