Sentence examples for in substantial problems from inspiring English sources

Chronic neck pain is one of the most common complaints in the general population and can result in substantial problems including the cost of treatment, disability and absence from work. 1 2 In many cases chronic neck pain is due to non-specific disorders of the muscles, tendons, joints and bones of the neck in association with unspecified degenerative changes.

Irrespective of different empirical frameworks, there are in general substantial problems in estimating growth-related econometric equations.

Stephen Walsh, the author of a magisterial, evenhanded biography of Stravinsky, describes in his introduction substantial problems of "factual or even textual accuracy" in the diaries, letters and other books published by Mr. Craft after Stravinsky's death.

In both samples more than half had substantial problems in cognition and functioning in Activities of Daily Living (ADLs).

However, this technique still possesses substantial problems in-terms of poor surface finish and dimensional accuracy of the prototypes.

Attention deficit hyperactivity disorder (ADHD) is a common disorder in children causing substantial problems for those afflicted [ 1- 3].

Variations in domain arrangement of formylglycinamidine ribonucleotide synthetase and substantial problems in aminoimidazole carboxamide ribonucleotide formyltransferase and inosine monophosphate cyclohydrolase assignments were also identified.

"While Infosys is not admitting any wrongdoing, its leadership did appreciate there were substantial problems in the way they were conducting business in this country," said John Malcolm Bales, the United States attorney for the Eastern District of Texas, in Plano.

The task force's recommendations come two months after a separate Board of Education study found substantial problems in the bilingual education program.

The fear is that this could not only harm the lab's already substantial problems in recruiting young scientists, but could cause an exodus of senior scientists fearful of heavy-handed government prosecutions.

Because of the intense local news coverage of the Muhammad trial, Mr. Horan, the Fairfax County prosecutor, said he expected "substantial problems" in trying to pick a jury for the Malvo case.