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Based on a careful analysis of theses structures, it is shown how the ligand-binding potency can be increased in subsequent design and synthesis steps.
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The artificial heart he developed is being used today, in subsequent designs, as a bridge to transplant in patients with heart failure.
His artificial heart — though it carried the name of a colleague, Dr. Robert Jarvik — is still in use, in subsequent designs, as a bridge to transplantation in patients with heart failure.
Much of the pressure drop was found to be in the device manifold which can be improved in subsequent designs.
In subsequent designs of the hip arthroplasty, a pink dental acrylic cement, circulated under the trade name of Nu-Life, to fix the stem to the bone was used.
This washout was first featured in the wing of the Type 224 and became a consistent feature in subsequent designs leading to the Spitfire.
"Nevada" was followed by 11 other battleships of this type, although significant improvements were made in subsequent designs as naval technology rapidly progressed.
The remaining alternatives can be analyzed in more detail in the subsequent design process, which increases design efficiency.
How to increase participant interaction will be an important issue in future research on social design feedback, as we assume that increased interaction also will increase the level of detail in the feedback and thus its value in the subsequent design process.
It can be seen that with this method it is possible to obtain both melting point and heat of fusion in a simple way which will be of great help in selecting heat storage material in solar-energy and industrial waste heat utilization and in the subsequent design of a thermal energy storage system.
The activities measured are shown in Figure 2 and in Additional file 2, which also show the activities of variants designed in two subsequent design cycles.
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