However, in addition, intermediate end points have been advocated for evaluation of intervention effects, as recently shown in studies evaluating drug effects on carotid or coronary atherosclerosis.
More and more, they seem to be used simultaneously in studies evaluating health interventions.
A "review of reviews" was undertaken to assess methodological issues in studies evaluating nondrug rehabilitation interventions in stroke patients.
Marked differences can be found in studies evaluating patients receiving ECMO for cardiovascular support when compared to ECMO for respiratory support.
This study became the reference standard for the PAC, with a precision of 15% being used in studies evaluating fluid responsiveness.
The OMS has been used primarily in studies evaluating locked IMN in which 68.8 % achieved good or excellent outcomes [28, 29, 32, 33].
These approaches are based upon studies showing a consistent pharmacogenetic response to regular use of SABAs and less consistent findings in studies evaluating LABAs.
Steady-state plasma concentrations of colistin, indirectly reflecting alveolar deposition, were significantly higher in studies evaluating high doses of nebulized CMS (4 5 MIU/8 h) [46, 47] compared to 2 MIU/8 h [45].
In fact, more or less similar amounts of bone formation have been reported in studies evaluating human sinus biopsies after grafting with a variety of biomaterials (bone formation ranging approximately from 30 to 50%) [19].
These results indicate some husbandry factors affect growth, sexual maturation and egg production in medaka and should be taken into consideration in studies evaluating endpoints that may be impacted by growth and reproductive performance, i.e. carcinogenesis and endocrine disruption studies.
To identify sources of heterogeneity (statistical, methodological, and clinical) in studies evaluating non-steroidal anti-inflammatory drugs (NSAIDs) vs acetaminophen in patients with knee and hip osteoarthritis (OA) to elucidate variations in outcomes.
