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Microarray analysis revealed a coordinated, down-regulated expression of protein biosynthesis genes in starved fish.
Total ash content and Zn residuals in whole-fish body were significantly highest in starved fish with Zn exposure.
In starved flies the GABABR2 knockdown results in a further increase of DILP-fluorescence (Fig. 4).
In starved fibroblasts, ERK1 turnover was 3.7 times slower than ERK2 turnover (ERK1: τ = 653 s; ERK2: τ = 178 s).
In starved NIM-1 cells, phospho-ERK decreased upon UO126 treatment, while phospho-AKT slightly increased (Fig. 5B).
Heme binding protein 1 was up-regulated in starved fish.
In starved individuals gluconeogenesis is the predominant metabolic pathway for energy production.
Two proteasome and 3 ubiquitin transcripts were also down-regulated in starved fish.
Collectively, these data suggest that iron homeostasis functions are compromised in starved fish.
Also, cGMP-dependent protein kinase (pkg) transcription was higher in starved females.
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We crossed females, either starved or in normal condition, with males, in starved or normal condition.
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