"in spite of this knowledge" is grammatically correct and commonly used in written English.
It is typically used to introduce a contrast or contradiction, as in the following example: In spite of this knowledge, she still chose to pursue her dream of becoming an artist. This phrase can also be used to emphasize the persistence or determination of the subject, as in: In spite of this knowledge, he continued to fight for justice. Other examples: - In spite of this knowledge, the company proceeded with the risky investment. - In spite of this knowledge, the team managed to win the championship. - In spite of this knowledge, the community remained divided on the issue. - In spite of this knowledge, he couldn't resist the temptation.
In spite of this knowledge, CSD remains an enigma necessitating further theoretical investigations.
In spite of this knowledge, neither companies nor students regularly get the most out of internships--not because companies are uncaring or want interns to do only grunt work or because students downplay the importance of internships.
However, in spite of this knowledge, the behavior persists.
In spite of this knowledge, diabetic retinopathy still occurs at an unacceptably high rate (4).
In spite of this knowledge, it was found only three multidrug-resistant isolates in 3-year survey.
21 In spite of this knowledge, systematic reviews and meta-analyses still provide summary data to policymakers, healthcare professionals, patients and their relatives to make decisions about the patients' treatment and well-being.
In spite of this common knowledge, smart people fall prey to the latest weight-loss fad because their hope overwhelms their common sense.
Being a Hindu vegetarian, in this light, is risky business, and I, along with many vegetarian Hindus accept the karmic blip we might incur in dining out in spite of the knowledge of potential meat contamination or accidental service.
M. Keith Booker, academic and author of studies about the implicit messages conveyed by media, views the character of Rourke as being motivated by "capitalist greed" when he pursues "his own financial gain" in spite of the knowledge that "his theft [of the crystal] will lead to the destruction of [Atlantis]".
If no religious intervention is instituted, the guilt-conscious Muslim society, and in particular the affected mother, may have to endure pain and suffering for years if the anomalous foetuses are left to proceed to term in spite of the knowledge bestowed upon the learned community that has the means at its disposal to prevent such catastrophes.
He knew of many atrocities that were already occurring, but, he said, "In spite of all this knowledge, it took me about 48 hours to convince myself that this information about a plan for total annihilation was to be taken seriously".
