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Thus, in spite of its ability to induce cell cycle arrest, p53 can act as a suppressor of cellular senescence when inhibits mTOR pathway [28], [29], [30], [31], [32], [33].
This combinatorial argument may explain the failure of the MBL model in practice, in spite of its ability to detect collective behaviors.
As PAC-1 killed p53 KO cells in spite of its ability to upregulate p53 in multiple cancer cell lines, we studied the role of p53 in PUMA upregulation.
Administration of either mAb to mCD16-/ tumor-bearing mice resulted in no anti-tumor activity, and this suggests that mFcγRIV, in spite of its ability to bind to WT and optimized Fc domains, plays no role in this tumor model, possibly because of its lack of expression on NK cells and its restricted expression to myeloid cells.
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In spite of its outstanding ability to control them, however, wet scrubbers have been considered as potential contaminant sources that may increase PCDD/DF concentrations in the flue gas.
"Hyaluronic acid was outside of the scope" of fever researchers, in spite of its already-documented ability to stimulate the immune system, Simon says.
In spite of its economic importance, the ability to modify and understand gene function in wheat is still not fully developed due to several limitations.
The disruptive healthcare innovation of the nurse practitioner, which the theory predicts should be scaling much more rapidly, still faces significant resistance from doctors and patients (although this might be a generational consideration as we have seen with our young army medics) in spite of its obvious economic benefits and its ability to get the job done.
More important, NBC Universal, in spite of its current malaise, has the ability to rebound sharply it is in the nature of TV networks to turn hot and then cold, and in the nature of film studios to have blockbusters and then flops.
In spite of its broad usefulness in providing the ability to develop new algorithms or to share and deploy new applications, the tree visualization part offered is, nevertheless, limited and cannot handle large amounts of data.
Notably, FC-POP CH2PEI FC-POP CH2PEI impressive CO2 storalsoability (3.2/2.6 mmol/g at 273/298 K) in spitexhibits poor BET surface area.
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