The model proposed by Wallander and Varni allows the identification of modifiable risk and protective factors in patients' adjustment by testing specified pathways (1) with a clear description of the role of disease-related and psychosocial factors.
Pathways listed are identified enriched pathways for indicated phenotypes; numbers in square brackets indicate the Kyoto Encyclopedia of Genes and Genomes (KEGG) identifiers for specified pathways.
The genes in the specified pathway are graphically represented as a color-coded diagram.
R i is the rank of the ith gene of the specified pathway in a list, r i is the absolute correlation value r.
WLS encodes an evolutionarily conserved transmembrane protein that genetically interacts with components involved in specified secretory pathways (Harterink et al, 2011; Silhankova et al, 2010; Yang et al, 2008).
Additional file 2 shows all metabolites and reactions involved in specified biochemical pathways, along with added reactions; it contains reaction properties such as name, ID, definition, equation, directionality, lower and upper bounds, enzyme commission (EC) numbers, ORFs, replaced reactions, and references.
Thus, the network is established without explicitly specifying pathways.
Here we describe the cellular pathways involved in the host response to experimental pneumococcal meningitis in specified disease states and brain regions.
Furthermore, we show that free Ptc (unbound by Hh) acts sub-stoichiometrically to suppress Smo activity and thus is critical in specifying the level of pathway activity.
In addition, we specified covariance pathways between latent attitude, perceived behavioral control, and norm variables.
