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Among the various possibilities known today for bestowing chirality to a metal surface only chiral modification by adsorbed chiral organic molecules (chiral modifiers) has gained practical relevance in catalysis, though its application range is still relatively narrow, confined to asymmetric hydrogenation of CO and CC bonds in specific substrates.
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Furthermore, it has been reported that the proline-rich region, which is uniquely present in PPP3CB, is involved in specific substrate selection because the affinity of PPP3CB to its substrates dramatically decreases after removal of the proline-rich region (Kilka et al. 2009).
Our results show that methylotrophic methanogenic archaea can survive in AGS if specific substrates, like methanol, are present in the wastewater.
Thus, the MRE β-loop could play a central role in cleaving specific substrates in this enzyme.
It is thought that UBA-UBL proteins exhibit some degree of selectivity in targeting specific substrates to the proteasome [ 20].
In these overexpression experiments wild-type N-terminus of PAPPA1 was processed by PCKS7 to comparable extent with FURIN, a finding that underscores again the limitations of this approach in identifying specific substrates.
In contrast, genome-wide approach may fall short in identifying tissue specific substrates for widely expressed PCSK enzymes.
A recent report demonstrated that LAPTM5 plays an important role in the lysosomal degradation of specific substrates in T cells [43].
Thus, the KIM, KIS and NXXKNRY motifs from PTP-SL interact with L16, α2L14 and L12 loops of ERK2, respectively, all involved in binding of specific substrates.
Peptidases_S8_3 and peptidases_S8_S53 domains might play a role in digesting the specific substrates for grape subtilases.
In addition, their specific substrates also include latent growth factors, growth factor binding proteins, chemokines and cell adhesion molecules.
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CEO of Professional Science Editing for Scientists @ prosciediting.com