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Immunohistochemical analysis of Rb distribution did not reveal any obvious alteration besides a decreased Rb signal in some nuclei of cells from subjects with HGPS (Figure S7).
TAMs had brown CD68 staining mainly in the cytoplasm, but also in some nuclei.
In some nuclei, several other weakly CMA3+ regions not corresponding to DAPI- signals mostly with pericentromeric locations were observed.
Staining decreased at 6 months in WT thyroid, but was unchanged in RET/PTC3 follicular cells (visible in some nuclei).
In postnatal stages, including the adult, some fibre cell nuclei appeared less PROX1-immunoreactive (not shown), and the fluorescence was barely detectable in some nuclei.
d-Mannose very weakly triggered the nuclear localization; strong GFP fluorescence was observed only in some nuclei at the concentration of 3 mM.
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The interesting material is not in some core nucleus, but rather interfacial across disciplines, be that traditional engineering and applied sciences, or business, medicine, law, etc. SEAS: Your thoughts on balancing the teaching and research missions?
It is evident that chromatin is aggregated in some nucleus regions, while other areas lack the presence of chromatin.
In addition, some nuclei showed a split SYCP3 signal along most of the X chromosome separated by a stretch of SYCP1, indicating that in these nuclei synapsis between sister chromatids of the X chromosome may occur.
In less organised aggregates, Ki-67 was present both in some trophoblastic nuclei and in nuclei of underlying nontrophoblastic cells that were positive for angiogenin).
In addition, H&E staining clearly showed the qualitative absence of nuclei in the bECM sections, whereas some nuclei can be observed in the bDBM sections.
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