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A therapy that apparently seems to work in some indication (or in some subpopulation) where it was previously either believed not to work, or had never been looked at, may simply be the result of a Type I error: a clear multiplicity issue.
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An ability to cross the placenta, which is also mediated, at least in part, by FcRn is desirable in some indications, such as feto-maternal alloimmune disorders.
This may be an advantage for the use of DKPs as peptide drugs in some indications, such as cancer or infectious diseases.
Herein, we briefly review the medical utilization of conventional, culture-derived MSCs and discuss whether these should be, in some indications, advantageously replaced by their prospectively selected perivascular ancestors.
However, early image acquisition 15 20 min after injection is useful in some indications, in particular MTC [ 14] or phaeochromocytoma [ 15].
The consequence is increased penetration of pathogens but also body cells and tissue, which may be wanted in some indications, e.g. in the eye for treatment of viral conjunctivitis [ 11, 43].
Von Schulthess et al. [ 27] suggest that the cost-effectiveness of integrated PET/CT is superior to that of PET alone in some indications, because of both the higher diagnostic accuracy of integrated PET/CT and the potential for higher patient throughput.
As CT has the highest sensitivity for detection of small pulmonary metastases, the indication for a PET/MR or a PET/CT examination has to be evaluated with care, and a CT of the thorax complementing a whole-body PET/MR will have to be considered in some indications.
The finding of complex apparatus at a death scene may provide useful information in ascertaining the manner of death and also in providing some indication as to the decedent's level of determination to succeed.
Nevertheless, our analysis of three candidate miRNAs by in-situ hybridisation gives some indication of cell type specific expression in mammary epithelial cells.
3, 17 A household survey conducted in 2002 provided some indication of water use and waste disposal in Jayapura.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com