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For comparison, in some determinations we included the organophosphate insecticide chlorpyrifos (CPF) as a positive control compound, because this agent is a known developmental neurotoxicant for which the PC12 model provides ready prediction of effects of in vivo exposure (Jameson et al. 2006; Qiao et al. 2001, 2005; Slotkin 2005; Slotkin et al. 2007a, 2007b).
NICE has taken the view that taxpayers, rather than patients, should be involved in decisions concerning the allocation of public funds for medical treatments and, in some determinations of utility values, panels made up of members of the public are used to elicit data [ 51].
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I think we have the opposite situation in this particular case, where the public health authorities may have information that may be of use and assistance to the animal health community in making some determination about how the disease progressed or the epidemiology of the disease.
It is only after the death of Hainuwele that human beings become sexual; that is, the murder of Hainuwele enables humankind to have some determination in the process of bringing new life into the world.
Giving up smoking is not the easiest thing in the world, but with some determination and support from your friends and family it is possible.
They reflect the growing, and in some quarters unexpected, determination of countries to act collectively.
The untested kits have collected in police evidence rooms amid tight budgets, overworked crime labs and, in some cases, the determination by some law enforcement agencies that there was insufficient cause to test a kit.
The ontological aspect of the categories consists in some kind of determination of their concreta.
"Until very recently, and sadly still in some countries, sex determination is based on grave goods.
Similarly, in a capital murder case, proof that a defendant suffers from an "intellectual disability" will spare a defendant from execution; in some states, this determination is made based largely on an arguably arbitrary IQ score cutoff (though the Supreme Court recently put some limits on this practice).
In some cases of determination of additives in diesel fuel, an additional step of fraction isolation was not necessary due to application of highly selective methods of final determination.
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