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Lastly, simple typographical errors of keying in the coordinates were observed in some annotations.
The hierarchical nature of the Gene Ontology resulted in some annotations being too general and frequent to be considered informative.
The absence of conserved residues such as histidines argues against the presence of heme cofactors in these C-subunits, contrary to what is claimed in some annotations.
Other databases such as KEGG (http://www.genome.jp/kegg/kegg2.html) [ 41] perform metabolic annotations, with fairly acceptable results, though failing in some annotations and missing several genes with metabolic functions.
Similar(56)
We find that ORF fragmentation has the potential to dramatically cause false-negatives in some annotation types, especially those relying on relatively small stretches of sequence (e.g., Pfam domains; Table 1).
Each feature can be understood as generating votes in favour of some annotations.
In addition, we performed a supervised in silico validation and biological interpretation of some annotations transferred in some selected biological examples.
We were also interested in whether some annotation with borderline hits close to the reporting threshold should be 'suppressed'suppressed
It is particularly well suited to collaborative environments in which some annotation tracks are public while others are restricted to individuals or groups, as GBrowse provides a highly configurable track-level security model that is able to integrate with a variety of popular enterprise authentication systems (gmod.org/wiki/GBrowse_Configuration/Authentication).org/wiki/GBrowse_Configuration/Authentication
But indeed, some of the enriched functional features here should be correlated with each other, for example some annotations in KEGG might be similar to those in GO Biological Process.
Some annotations in text.
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