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The scenarios were tested in single dose and steady state studies.
Moreover, a relatively larger dose was used in patients who received the repeated dose (100 140 U compared to 70 100 U in single dose group).
Parent drug in single dose is the most sensitive analyte and study design for bioequivalence trials in almost all the studied scenarios.
Information on tramadol hydrochloride 75 mg in single dose studies is limited and variable [16, 17], but the wide confidence interval around the measured NNT of 6.7 (3.5 to 60) encompasses existing estimates.
In this study, we have evaluated the capacity of CER-001 to perform reverse lipid transport in single dose studies as well as to regress atherosclerosis in LDLr−/− mice after short-term multiple-dose infusions.
The lyophilized FMP2.1 antigen, Lot #1046, was packaged in single dose vials of approximately 60 µg.
Similar(28)
Levalbuterol, however, was available exclusively in single-dose containers, requiring individual retrieval from our computerized system.
Prada's unisex line, for example, focuses on treatment, offering moisturizers, sun-shielding creams and exfoliants in single-dose packets.
Compounds 10 13, 22, and 23 possessing urea spacer exerted lethal effect over the NCI-60 panel with mean %inhibitions more than 100% in single-dose testing.
To assess whether success rate differs in single-dose versus multiple-dose administration of methotrexate (MTX) in medical management of unruptured ectopic pregnancies.
New requirements in single-dose investigations have also been suggested by the EMA to address the absence of a parameter that can adequately assess the equivalence of the shape of the curves.
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