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Lamarckism a school of thought named for the 19th-century pioneer French biologist and evolutionist Jean-Baptiste de Monet, chevalier de Lamarck assumed that characters acquired during an individual's life are inherited by his progeny, or, to put it in modern terms, that the modifications wrought by the environment in the phenotype are reflected in similar changes in the genotype.
Pre-treatment by autoclaving and drying at 160°C resulted in similar changes.
sEH inhibition increased some lipoxygenase products and resulted in similar changes as observed with the broad-spectrum CYP450 inhibitor fenbendazole.
In particular, a linear Notch pathway would predict that deletion of RBP-J [30], [75] would result in similar changes as would Notch blockade by γ-secretase inhibitors, or even by over-expression of dominant-negative (DN) MAML [78].
Moreover, knock down of the non-canonical Wnt11 that induced similar phenotypes as the Fyn and Yes knock downs [13] resulted in similar changes in the PTK activity profile.
In order to determine whether altering IGF-I levels in the whole organism results in similar changes in autophagy as those observed in culture, we examined mice that produce reduced levels of IGF-I.
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In addition, the malfunction of multiple reactions/preexisting molecules may result in similar change in the profiles of STAT3N ∗ -STAT3N ∗ and SOCS3.
Since all instruments were scored identically and resulted in similar change scores, the exact level of MCID chosen is of only peripheral relevance.
The binding of curcumin or resveratrol results in several similar changes in specific H N chemical shifts of Aβ42.
As for IGFBP-1, the four insulin preparations resulted in virtually similar changes in IGFBP-2 levels, regardless of glycemic control.
In fact, similar changes took place independently in different lineages[ 14].
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