Sentence examples for in silico computed from inspiring English sources

Genes, metabolites, lipids, and in silico computed reaction fluxes were defined as nodes.

Yang et al. [ 19] also created a publicly available database of Differentially Expressed MiRNAs in human Cancers (dbDEMC) with the goal to provide potential cancer-related miRNAs by in silico computing.

All possible single mutants at TEV UTRUTR sequence were generated in silico and computed to obtain their minimum free energy secondary structure (MFESS) using the RNAfold program from the ViennaRNA package version 1.6.4.

There he learned that "in silico" they were test-driving vehicles, running them through scenarios in simulation before testing them on the track or the open road.

Model-development is an iterative process that moves from a genome annotation and biochemistry of the organism to the development of a genome-scale metabolic network that can be used as a fully functional in silico organism to compute physiological phenotypes.

Moreover, compensation for OP-R deficiency in orchards could be achieved by supplementing suitable pollinizers computed in silico.

By consecutively shifting the enzymes' V max and K m values and using the normal state as control, relative changes of in silico butanol production were computed.

Figure  4 shows the relationship between in vivo fitness and the size of the structural perturbation d ij, computed in silico as the Hamming distance between the structure shown in Fig.  1b and the MFESS obtained for each mutant.

The drug response data used in this analysis was measured in various ways: (a) ATP concentrations (HapMap dataset): In this case the in silico drug response is computed via MOMA in two steps; (1) obtaining a wild-type flux distribution via Flux Balance Analysis in which the corresponding drug target reaction is initially forced to be active (the pre-drug condition).

In silico drug response is computed according to the biological phenotype measured experimentally, which in this case includes ATP levels, or AC50/IC50 values (the concentration at which a given compound exhibits half-maximal efficacy or half-maximal inhibition of cell growth, respectively).

The high epitope density of SP was computed using in-silico methods and corroborated by the high percentage of identified SP epitope in the IEDB (immune epitope database).