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At the same time tubulin oligomers will participate considerably in sheet formation and MT elongation just as they do during early nucleation stages by laterally associating with longer protofilament overhangs within the sheet.
Expression of a constitutively active mutant form of R-Ras (38V) resulted in a dramatic increase in sheet formation by the oligodendrocytes (Fig 3C).
Because Mn2+ acts directly on the integrin ligand binding domain, we can conclude that the increase in sheet formation reflects a direct effect on the integrin and therefore on the equilibrium between inactive and active integrins, rather than via modulation of separate downstream signalling pathways.
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MAG expression appears to extend further to the periphery of OL processes suggesting that MAG expression precedes MBP in outer sheet formation of human fetal OLs.
Pif-177 also takes part in lamellar sheet formation and therefore it is an essential component of the organic matrix for normal growth of the nacreous layer [ 62].
Amyloidosis is a disease characterised by the deposition in body tissues of amyloid: abnormal protein in a beta pleated sheet formation.
Increasing levels of outside-in signalling via the laminin receptor α6β1 integrin were found to promote oligodendrocyte processing and myelin sheet formation in culture.
& Otto, A. Thin current sheet formation in response to the loading and the depletion of magnetic flux during the substorm growth phase.
Further, inertia-based asymmetry is studied and an analytical method is proposed (L1 error norm = 0.05) to understand the deflection observed in the plane of sheet formation.
This analysis further confirmed the ability of EphA4 and EphB1 to stimulate myelin sheet formation in the oligodendrocytes).
Forward and reverse signaling through the Eph-ephrin receptors have opposite effects on process extension and myelin sheet formation in oligodendrocytes.
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