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In particular it has been shown that p27 expression is regulated by a proteasome-dependent degradation [4] and that this mechanism plays a pivotal role in the regulation of p27 expression in several type of human tumors, as first demonstrated in breast and colon cancer [5] [6].
While some in vitro studies have reported a protective role of SOD2 against tumor progression in several type of cancer cell lines [ 21- 26], in vivo studies suggest more complicated roles of SOD2 in tumorigenesis.
Annexin A2 shows increased expression in several type of cancer, including renal cell cancer (Zimmermann et al, 2004a), breast cancer (Sharma et al, 2006) and sarcomas (Gillette et al, 2004; Syed et al, 2007), and there are several possible mechanisms by which annexin A2 may be involved in tumour progression.
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Casein kinase 2 (CK2) is overexpressed in several types of cancer.
Layout problems are found in several types of manufacturing systems.
Consistently, downregulation of miR-124 was observed in several types of human cancers20,21,22,23,24,25.
Previous studies have identified PHLPP as a tumor suppressor in several types of cancer.
In several types of animals, muscle cells use membrane extensions to contact motor axons during development.
Many studies have shown that extended television watching can produce a decline in several types of mental ability.
However, these holes are also found in several types of lizard and snake – not animals famous for their whiskers.
The involvement of p62-related signaling in CSC maintenance has been demonstrated in several types of cancer cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com