This task can be as tedious as searching for every predicted interaction in several interaction data repositories, or manually screening the scientific literature.
However, as Goh and his colleagues reported, in several interaction networks that they examined, the betweenness of a node is correlated to its degree [ 46].
In cluster headache several interactions between sleep and the severe pain attacks have already been proposed.
In contrast to section, which focused on individual steps, in complex systems, several interactions between chemicals and biosystem components participate in the overall outcome.
In order to understand the associations that lead to an observed phenotype in human diseases, several interactions have been explored and several strategies have been developed in order to analyse the information contained in these disease network.
As shown in Figure 3, several interactions between autophagy and other signaling pathways have been recognized to play a functional role in tumorigenesis.
This study includes both experimental and predicted interaction of human proteins for the generation of disease-protein network, considering the successfulness of predicted interactions in several disease interaction studies [ 5, 28].
The analogues that make several interactions in the molecular docking studies were synthesized in the laboratory for further studies [13].
Moreover, although factors contributing to the geographic differentiation of coevolutionary interactions have been discussed in several interspecific interactions [ 9, 34- 36], no study has tested whether such factors could differ, or are the same, among spatial scales.
