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The role of fitness deficits and compensation for variant selection and persistence is discussed together with technical issues in sequencing as well as clinical implications in the use of DAAs now and in the future.
To account for noise (error rates in sequencing as well as mapability issues) in the raw sequencing data as well as potential missorting of individuals in the mutant pool, relatively loose criteria (>70% non-reference alleles) were applied for candidate mutations.
In mammals, miRNA editing events in which adenosine is converted to inosine by adenosine deaminases (ADARs) are observed for several miRNAs; the resultant inosine is detected in sequencing as an A-to-G conversion [ 10, 12, 47- 49].
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Read in sequence, as following hard upon "At Swim-Two-Birds," it can be appreciated as equally fantastic and original but more coherent, with a story line that rouses suspense and comes, in irregular fashion, full circle.
When natural fifths are constructed in sequence, as from C to G to D..., a circle back to C (=B♯) occurs:... A♯, E♯, B♯.
In the following days another article started to circulate showing original contact sheets from film negatives, in sequence, as taken by the photographer, Danny Lyon, who was there in 1962.
By incorporating differences in sequence as well as frequency, haplotype relationships can be graphically depicted in a Median Joining network (Figure 2B).
Functional genomic surveys of pathogen effectors have indicated that these proteins are highly diverse in sequence, as well as in molecular function [ 12- 14].
46 such positions were identified, not considering the C-terminal region where most of the copies differ in sequence as well as in length.
In summary, we found four NB-LRR genes conserved in sequence as well as linked to structurally immobile parts of the core-eudicot pan-genome.
Each returned questionnaire was given a number, in sequence, as a unique identifier and the data were entered into an Access database.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com