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In fact, the range of variation is 2.6‰ in the δO PO4 and 5.6‰ in the δO CO3 for the samples from the same specimen.
We sequenced matching DNA and RNA samples retrieved from the same specimen.
Isolating different viruses from multiple cultures from the same specimen should be the gold-standard method for determining co-infection of a sample.
The failure to isolate the organism from the same specimen where D. pigrum DNA was PCR-amplified in one patient may be due to the inhibitory effect on growth of local antibiotic treatment prior to corneal sampling.
The final samples employed were, in fact, the same ones as in Sanchez et al. 14 to assure that all data were from the same specimens.
To examine KCNJ6 gene expression levels, a total of 105 human DNA samples extracted from human occipital cortex and 100 RNA samples extracted from human anterior cingulate cortex of the same specimens were additionally obtained from the Stanley Medical Research Institute (Bethesda, MD) as samples independent of that in the association study (SMRI samples).
The same samples were analysed for mutations in the p53 DNA binding domain and of the p53 codon 72 SNP, using snap frozen cells from the same specimens.
DNA for 13 tumors and 17 normal samples were re-extracted from a different isolate while the same specimens were used for the remaining 20 tumors and 16 normal samples.
This approach has many advantages, such as allowing a comparison between samples from the same individual, often from a single larger tissue specimen, thus reducing individual-specific and anatomical site-specific effects.
The same specimen as in Fig. 3b.
The same specimen processing protocol was used for all samples.
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