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Matrigel culture resulted in reversion of activated PSCs to a quiescent-like state.
The path towards pure spontaneity thus consists always in reversion or undoing.
A fivefold increase in reversion frequency when cytochrome b5 was coexpressed with P450 reductase was abolished by disruption of heme-binding in cytochrome b5 by site-directed mutagenesis (His68Ala), suggesting that electron transfer to cytochrome b5 was necessary for the stimulation.
Man's concern with taming wild land, or advancing frontiers, or finding therapy in reversion from the civilized life to the atavistic is well reflected in adventure novels, beginning with James Fenimore Cooper's novels of the American frontier The Pioneers (1823) and The Last of the Mohicans (1826).
This resulted in reversion to sinus tachycardia at 145/min.
In this process, a mutation at the dominant allele for female sterility or a recombination of the two sterility loci results in reversion to hermaphroditism (Charlesworth, 2002).
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Only one report has documented an in-patient reversion of an isogenic strain from INH resistant to susceptible [ 52].
So what we know in mean reversion in height is tall parents will tend to have tall children, but not quite as tall as them.
Disrupting tumor cell interaction with the ECM via integrin blocking antibodies resulted in phenotypic reversion in a breast cancer model [ 52].
Remarkably, downregulation of the latter also results in floral reversion (which occurs in ovaries) and alters inflorescence architecture by switching off terminal, determinate growth.
Concretely, in the reversion experiments depicted in Figure 5, we show that the expression of shRNAs against REST rescue the effects triggered by the sponge.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com