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This method is based on the generation of an orthogonal tRNA/aminoacyl-tRNA synthetase (aaRS) pair that allows the site-selective incorporation of unnatural amino acids into proteins in response to unique nonsense and frameshift codons.
Hence, Gβγ-mediated PKD activation seems to be a specific function in response to unique Gβγ combinations.
Altogether, this suggests that the expansion of the HyHK family in Azospirillum may have arisen in response to unique challenges that members of this genus faced.
Hence, genomic rearrangement may contribute to rapid evolution along the human and/or higher primate lineages in response to unique physiological constraints.
Briefly, orthogonal tRNA-aminoacyl-tRNAsynthetases (tRNA-aaRS), which are engineered to incorporate UAAs in response to unique codons, such as the amber stop codon TAG, are introduced into live cells.
Orthogonal tRNA-aminoacyl-tRNA synthetase pairs are widely used for the site-specific incorporation of nearly 80 unnatural amino acids (unAAs) in Escherichia coli, Saccharomyces cerevisiae, plant, and mammalian cells in response to unique nonsense (e.g., amber) and frameshift (e.g., quadruplet) codons.
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Generally, states have been flexible in their response to unique local situations because mandating uniform programs on a national level cannot provide the differentiated instruction needed to meet the needs of individual children with varying abilities.
The constructed box was shown to have a unique reclosing mechanism, which enabled it to repeatedly open and close in response to a unique set of DNA or RNA keys.
We are shaping the future of each of our publishing businesses in response to the unique market environments in which they operate.
Evolution sculpts the olfactory nervous system in response to the unique sensory challenges facing each species.
In response to the unique, and then unmet, needs of child-bearing women, new sources of government information were developed.
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