The part of the sentence 'in response to these changes' is correct and usable in written English.
You can use this phrase when you want to communicate something that has happened or taken place in reaction to something else. For example, "The company issued a statement in response to these changes, outlining their plans for the future of the business."
At the same time, there are clear indications that the health system and the health needs of the population are changing and that government must modify policies in response to these changes and shape a health system that can cope with the future.
In response to these changes, copyright holders have sought greater protection through legal and technological remedies.
In response to these changes, Greek polities undertook colonial foundations, first in the Aegean and subsequently in Italy.
In response to these changes, retailers and their supply-chain partners will need to rethink their competitive strategies.
In response to these changes, fiction, too, became climate-controlled: in the modern novel, as in modern housing, outside conditions seldom intruded.
In their benchmark analysis, they allow people to move around as they like in response to these changes.
The combination of the changes in energy prices and the changes in demand for energy in response to these price changes leads to changes in overall energy expenditures.
They had to press a button in response to these luminance changes (with response hand changing from left to right, or vice versa, for each successive block).
Monthly surveys will assess how each person's attitudes, perceived social norms and behavior develop in response to these perceived changes in social norms.
And in response to these structural changes, Americans have developed a culture around sugar, based on the belief that it is a food rather than a drug.
A second version of One Rincon Hill was proposed in response to these zoning changes, in which the height was increased to 60 stories.
