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The government has insisted, for example, that the companies with which the NSA partners under the Prism program don't simply permit intelligence agencies to troll through their systems and servers hunting for malefactors: they provide the government with user data only in response to targeted requests that use a specific "hard selector" like an e-mail address or user ID.
T-cell activation in response to targeted Ag-laden microspheres is 10- to 100-fold greater than the response to the non-targeted Ag-laden microspheres.
At the national level, the Defense Department is a very active early adopter, focused on using Web services to help increase flexibility to deploy military resources in response to targeted threats.
On the basis of these findings, we propose that cSMART displays the diagnostic hallmarks of a comprehensive plasma genotyping assay, with potential application for precisely monitoring changes in plasma mutation levels in response to targeted drug therapy.
Thus, although our data clearly show that many tumor cells die in response to targeted toxins by activating efficient and rapid death pathways such as necroptosis or apoptosis, the drugs may be effective even if these pathways are blocked.
Additionally, we previously found that certain cell lines that don't activate caspases at all in response to targeted DT may die by a slow cell death mechanism that does not involve the release of cytosolic proteins that occurs in necroptosis [16], [19].
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Electric current (I) measurements in response to target binding events in pure serial diluted samples of E. coli and S. aureus at each junction within the 2×2 array were monitored to create calibration curves.
Embedded gramicidin A (gA) ionchannels in a self-assembled tethered lipid bilayer act as biological switches in response to target molecules and provide a signal amplification mechanism that results in high sensitivity molecular detection.
We note that the optimal characteristics of probes for gene family detection differ greatly from those for applications such as gene expression, in which mismatch bases are not tolerated and ideal probes produce linear signals in response to target concentration.
Therefore, we provide the first demonstration of the role of cellular senescence in response to targeting Mdmx in BrCa in vivo.
To characterize an external RNA transcript response we can describe signal in response to target concentration by the following general function.
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