We therefore, also adjusted the random-effects models for the design effect (which was reported in relevant trials) from cluster-randomized trials.
The range-of-motion criterium was used in order to obtain a study population that would resemble study populations in relevant trials where the SPADI has been employed as an outcome measure.
20 Sixth, while recommendations are relatively similar in young children, older children and adults, the evidence for the former is weaker due to the under-representation of preschool-aged children in relevant trials.
First was patient equity: patient advocacy groups had long lobbied for a registry to help patients gain access to up-to-date information about potentially life-saving therapies and have the opportunity to enrol in relevant trials.
However, the cross sectional design adopted herein cannot prove definite causality and it is likely that the number of hospital admissions as well as the length of hospitalisation is mediated by many different factors, which have to be investigated in relevant trials.
One speculative hypothesis, that we discuss further below is that a sustained encoding and maintenance of task goal value may be more important in the Money block, because in this block the incentive cues themselves may not be as effective in conveying the relevant trial reward value.
The second application used poor recruitment rates reported in previous relevant trials included in a systematic review to determine site selection criteria (application 10).
First, high MgSO4 doses formerly used for tocolysis were associated with neonatal hypermagnesemia, hypotonia, resuscitation, and mortality [ 8], but no such effects were seen when MgSO4 was used at lower doses for fetal neuroprotection in the relevant trials or in subsequent publications [ 9].
The reviewers believe the search strategy to be comprehensive and to have been successful in locating relevant trials for inclusion in the review.
21 The only relevant trial in the literature used intrauterine insemination cycles as the unit of analysis and a crossover design but did not provide outcome data from before the crossover.
