We observed no notable effect of arsenic on cell type proportions, except for moderate estimated percent decreases in CD4+ T cells and natural killer (NK) cells in relation to the highest quartile of urinary total arsenic concentration as well as borderline associations (p = 0.13 0.14) in relation to the highest quartile of blood arsenic concentration.
Cardiovascular risk factors at the baseline examination in relation to the sex-specific quartiles of cadmium are presented in table 1. Age, hsCRP, HDL, plasma creatinine, systolic blood pressure, history of diabetes, history of a coronary event, current smoking, high alcohol intake, being unmarried and low educational level were significantly associated with the cadmium level, table 1.
No obvious dose-response relation is evident for SES score in relation to risk, although all groups are estimated to have elevated odds of the outcomes in relation to the most advantaged SES quartile.
Poisson regression with robust estimation of variance was used in bivariate and multivariable analysis to estimate the prevalence ratios (PR) of the independent variables (socioeconomic and demographic factors) in relation to the outcomes, with the dependent variables (dietary patterns) being classified as dichotomous: 1st, 2nd and 3rd quartiles of consumption and high consumption (4th quartile).
Linear regression was used to evaluate the association between quartiles of arsenic exposure, based on the distribution in our study sample, in relation to the estimated cell type fractions adjusted for sex and age.
In relation to the previous step, RAVE.
Moreover, the risk of breast cancer in relation to T3 quartiles was analyzed in different strata of TSH (below and above the median).
Clinical and laboratory characteristics of the study group in relation to quartiles of serum TXB2 concentration are shown in Tables 1 and 2. Patient recruitment began in January 2008, which explains why only two-thirds of the patients received metformin (according to the guidelines valid at the time, metformin had not yet been recommended for the majority of patients with DM2).
Even after excluding 611 subjects with antidiabetic treatment or insulin injection, the odds ratio of the risk of type 2 diabetes in relation to quartiles of serum fetuin-A concentrations increased when adjusted for age, sex, community, current smoking, current drinking, BMI, WHR, blood pressure, TC, logTG, HDL-C, LDL-C and logCRP (OR 1.19, 95% CI 1.01 1.40, p = 0.04).
We used unconditional logistic regression to estimate the odds ratios (ORs) for QTc prolongation in relation to quartiles of baseline well-water and urinary arsenic.
