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However, there is significant overlap in the systems that were manipulated in relation to studying the phenotypes individually.
This is why it was argued that observational studies have a limited role in relation to studying weak effects (Taubes 1995).
In relation to studying the role of the TGF-β-induced EMT in breast cancer progression in particular, the nontransformed NMuMG and EpH4 mouse mammary epithelial cell lines are the most commonly used models.
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Our discussion extends to both methodological issues in relation to study design and to pragmatic issues relating to the execution of RCTs.
Our findings should be considered in relation to study limitations.
Fig. 1 Study country Kenya (top right) in relation to study area—Tana.
There was significant heterogeneity between studies in relation to study design and laboratory methodology, complicating direct comparisons.
To study treatment modalities for cesarean scar pregnancies (CSPs), focusing on efficacy and complications in relation to study quality.
Nine were considered relevant and evaluated in relation to study design using a standardized study checklist and levels of evidence.
In relation to study reliability, internal consistency checks were used by all studies and test-retest reliability was the second most commonly used technique (22.8%, n = 24).
We identified significant sources of potential bias in both directions in relation to study design and implementation fidelity that have not been quantified previously.
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