Note the overall logarithm change occurring in relation to cycle number.
Male responses did not differ in relation to cycle stage.
The tumour burden was evaluated before the start of second-line chemotherapy (cycle 1) and, thereafter by every second cycle of chemotherapy, that is, in relation to cycles 3, 5, 7, etc.
Because of the uncertainty about the relative importance of genetic and epigenetic mechanisms, we investigated potential effects of furan on gene expression in relation to cell cycle, apoptosis, and DNA damage, and we assessed potential changes in DNA methylation and microRNA (miRNA) expression.
The detailed mechanism by which survivin influences cell fate following TGF- β treatment requires further study in relation to cell cycle status and regulators, the chromosomal passenger complex with Aurora B, microtubule dynamics, and caspase activity.
Our study suggest that other partners of the intracellular metabolism of gemcitabine in relation to cell cycle effects and DNA repair could be more responsible for the radiosensitising effect of gemcitabine than dCK activity of the cell.
The effects of 5-fluorouracil (5-FU), doxorubicin and paclitaxel on FDG and FLT uptake were measured in MDA MB231 human breast cancer cells in relation to cell cycle distribution, expression and enzyme activity of TK-1.
Chen et al (2003) examined the optimal timing of PTX treatment and irradiation in relation to the cell cycle, and recommended that radiation be given at least 5 h after PTX administration, because G2/M arrest of a lung cancer cell line was shown to start at 4 h after PTX treatment and to last for 44 h.
This is evaluated in relation to cell-cycle response and repair of ICL damage using DNA-repair-deficient Chinese hamster ovary (CHO) cell lines and human cervix carcinoma (HeLa) cells.
Oxytocin is released in a pulsatile manner and may also vary in relation to the menstrual cycle and use of oral contraceptives.
Together, these examples demonstrate that cumulus cells perform key functions on behalf of oocytes and act as a nexus by responding to oocyte and maternal stimuli to coordinate oocyte maturation in relation to the reproductive cycle and follicle development (reviewed in Ref. 183).
